Article
HLA-B16 antigens: sequence of the ST-16 antigen, further definition of two B38 subtypes and evidence for convergent evolution of B*3902.
Tissue antigens - 1 Jan 1995
Adams E J, Martinez-Naves E, Arnett K L, Little A M, Tyan D B, Parham P
Abstract excerpt
The ST-16 antigenic specificity of the HLA-B locus is defined as a B39 variant of Mexican-Americans. Nucleotide sequencing of cDNA shows the ST-16 allele (B*3905) differs from B*39011 by a single substitution that substitutes tyrosine for aspartic acid at position 74 of the mature class I heavy c...
Topics
- Alleles
- Amino Acid Sequence
- B-Lymphocytes
- Base Sequence
- Biological Evolution
- Cell Line, Transformed
- DNA, Complementary
- HLA-B Antigens
- Humans
- Mexican Americans
- Molecular Sequence Data
- Sequence Alignment