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Article

Requirement of FGF-4 for postimplantation mouse development.

Science (New York, N.Y.) - 13 Jan 1995

Feldman B, Poueymirou W, Papaioannou V E, DeChiara T M, Goldfarb M

Abstract excerpt

Fibroblast growth factors (FGFs) are thought to influence many processes in vertebrate development because of their diverse sites of expression and wide range of biological activities in in vitro culture systems. As a means of elucidating embryonic functions of FGF-4, gene targeting was used to generate mice harboring a disrupted Fgf4 gene. Embryos homozygous for the null allele underwent uterine implantation and...

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Identifiers

PMID: 7809630
DOI: 10.1126/science.7809630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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