Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibroblast growth factor receptor two (FGFR2) regulates uterine epithelial integrity and fertility in mice.

Biology of reproduction - 1 Jan 2014

Filant Justyna, DeMayo Franco J, Pru James K, Lydon John P, Spencer Thomas E

Abstract excerpt

Fibroblast growth factors (FGFs) and their receptors (FGFRs) regulate luminal epithelial (LE) cell proliferation in the adult mouse uterus. This study tested the hypothesis that FGFR2 has a biological role in postnatal development and function of the uterus by conditionally deleting Fgfr2 after birth using progesterone receptor (Pgr)-Cre mice. Adult Fgfr2 mutant female mice were initially subfertile and became...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryo Implantation
Share to Embryo Loss
Share to Epithelial Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fertility

Share to Mice, Transgenic

Share to Pregnancy

Share to Receptor, Fibroblast Growth Factor, Type 2

Share to Uterus

Source

Open in PubMed Open full text

Identifiers

PMID: 24227756
DOI: 10.1095/biolreprod.113.114496
PMCID: PMC7289345

Genes

FGFR2
KRT14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibroblast growth factor receptor two (FGFR2) regulates uterine epithelial integrity and fertility in mice.PMID 24227756Read ↗

Lactoferrin-iCre: A New Mouse Line to Study Uterine Epithelial Gene FunctionSemantic proximity Read ↗

The Epidermal Growth Factor Receptor Critically Regulates Endometrial Function during Early PregnancySemantic proximity Read ↗

Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract.Semantic proximity Read ↗

Illuminating the “Black Box” of Progesterone-Dependent Embryo Implantation Using Engineered MiceSemantic proximity Read ↗

Uterine stromal but not epithelial PTGS2 is critical for murine pregnancy successSemantic proximity Read ↗

Forkhead box a2 (FOXA2) is essential for uterine function and fertilitySemantic proximity Read ↗

Increased FOXL2 Expression Alters Uterine Structures and FunctionsSemantic proximity Read ↗

COUP-TFII Mediates Progesterone Regulation of Uterine Implantation by Controlling ER ActivitySemantic proximity Read ↗

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction.Semantic proximity Read ↗

Development of the mammalian urethra is controlled by Fgfr2-IIIbSemantic proximity Read ↗

Fgfr2 is integral for bladder mesenchyme patterning and function.Semantic proximity Read ↗

Integrated chromatin immunoprecipitation sequencing and microarray analysis identifies FOXA2 target genes in the glands of the mouse uterusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.