Article
Murine FGFR-1 is required for early postimplantation growth and axial organization.
Genes & development - 15 Dec 1994
Deng C X, Wynshaw-Boris A, Shen M M, Daugherty C, Ornitz D M, Leder P
Abstract excerpt
We have explored the role of fibroblast growth factor receptor 1 (FGFR-1) in early embryonic development using three experimental systems: genetically deficient mice, in vitro blastocyst culture, and FGFR-1-deficient embryonic stem cells. Using these systems, we demonstrate that FGFR-1 is require...
Topics
- Animals
- Base Sequence
- Blastocyst
- Cell Differentiation
- DNA Primers
- Embryonic and Fetal Development
- Exons
- Fetal Growth Retardation
- Fibroblast Growth Factors
- Genetic Vectors
- Genotype
- Homozygote
- In Situ Hybridization
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data
- Receptor Protein-Tyrosine Kinases
- Receptor, Fibroblast Growth Factor, Type 1