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Article

Murine FGFR-1 is required for early postimplantation growth and axial organization.

Genes & development - 15 Dec 1994

Deng C X, Wynshaw-Boris A, Shen M M, Daugherty C, Ornitz D M, Leder P

Abstract excerpt

We have explored the role of fibroblast growth factor receptor 1 (FGFR-1) in early embryonic development using three experimental systems: genetically deficient mice, in vitro blastocyst culture, and FGFR-1-deficient embryonic stem cells. Using these systems, we demonstrate that FGFR-1 is required for proper embryonic cell proliferation and for the correct axial organization of early postimplantation embryos but...

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PMID: 8001823
DOI: 10.1101/gad.8.24.3045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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