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Article

BMP type II receptor is required for gastrulation and early development of mouse embryos.

Developmental biology - 1 May 2000

Beppu H, Kawabata M, Hamamoto T, Chytil A, Minowa O, Noda T, Miyazono K

Abstract excerpt

Bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta superfamily, play a variety of roles during mouse development. BMP type II receptor (BMPR-II) is a type II serine/threonine kinase receptor, which transduces signals for BMPs through heteromeric complexes with type I receptors, including activin receptor-like kinase 2 (ALK2), ALK3/BMPR-IA, and ALK6/BMPR-IB. To elucidate the...

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Identifiers

PMID: 10772805
DOI: 10.1006/dbio.2000.9670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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