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Article

Physiology and pathology of islet metabolism.

Diabete & metabolisme - 1 Jan 2000

Malaisse W J

Abstract excerpt

This review reevaluates the possible roles of glut-2 underexpression, glucokinase gene mutation, glucose-6-phosphate hyperactivity, glycerophosphate dehydrogenase (FAD-linked) deficiency and glycogen accumulation in the pancreatic B-cell as contributive factors in the pathogenesis of Type 2 diabetes.

Topics

Animals
Glucokinase
Glucose Transporter Type 2
Glucose-6-Phosphate
Glucosephosphates
Glycerolphosphate Dehydrogenase
Glycogen
Islets of Langerhans
Monosaccharide Transport Proteins
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7805957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7805957-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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