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Article

Pathogenesis of type 2 diabetes mellitus.

Archives of medical research - 1 Jan 2000

Leahy Jack L

Abstract excerpt

The pathological sequence for type 2 diabetes is complex and entails many different elements that act in concert to cause that disease. This review proposes a sequence of events and how they interact by a careful analysis of the human and animal model literature. A genetic predisposition must exist, although to date very little is known about specific genetic defects in this disease. Whether the diabetes...

Topics

Animals
Diabetes Mellitus, Type 2
Environment
Fatty Acids
Genetic Predisposition to Disease
Glucose
Humans
Insulin
Insulin Resistance
Islets of Langerhans
Life Style
Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15925010
DOI: 10.1016/j.arcmed.2005.01.003

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