Article
[Diabetogenes; which cause type II diabetes mellitus].
Rinsho byori. The Japanese journal of clinical pathology - 1 Aug 1995
Murakami T, Shima K
Abstract excerpt
Glucose homeostasis depends upon a balance between glucose production by the liver and glucose utilization by insulin-dependent tissues, such as muscle and fat. Insulin, secreted by the pancreatic B cell, inhibits hepatic glucose output and facilitates glucose utilization in the muscle and fat tissues. In the diabetic patients, there are three types of pathological defects; (1) inability of the B cell to secrete...
Topics
- Animals
- Diabetes Mellitus, Type 2
- Glucokinase
- Humans
- Insulin
- Mutation
- RNA
- RNA, Mitochondrial
- Receptor, Insulin