Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pathophysiology of type 2 diabetes: targeting islet cell dysfunction.

The Journal of the American Osteopathic Association - 1 Mar 2010

Spellman Craig W

Abstract excerpt

Type 2 diabetes mellitus (T2DM) continues to be a major health problem worldwide. It is well known that T2DM is a metabolic disorder characterized by hyperglycemia, which arises from insufficient pancreatic insulin secretion, insulin resistance in peripheral tissues, and inadequate suppression of glucagon production. This suppression results in inadequate uptake, storage, and disposal of ingested glucose...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Dietary Carbohydrates
Share to Global Health

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glucagon

Share to Glucose

Share to Insulin Resistance

Share to Insulin-Secreting Cells

Share to Insulin Secretion

Source

Identifiers

PMID: 20382838

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pathophysiology of type 2 diabetes: targeting islet cell dysfunction.PMID 20382838Read ↗

Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies.Semantic proximity Read ↗

Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future.Semantic proximity Read ↗

Pathogenesis of type 2 diabetes mellitus.Semantic proximity Read ↗

Pancreatic β-Cells and Type 2 Diabetes DevelopmentSemantic proximity Read ↗

Pathogenesis of type 2 diabetes mellitus.Semantic proximity Read ↗

The pathophysiology of type 2 diabetes mellitus: an overview.Semantic proximity Read ↗

Multifaceted therapeutic approaches for a multigenic disease.Semantic proximity Read ↗

Beta-cell dysfunction and insulin resistance in type 2 diabetes: role of metabolic and genetic abnormalities.Semantic proximity Read ↗

IRS2 takes center stage in the development of type 2 diabetes.Semantic proximity Read ↗

Type 2 diabetes across generations: from pathophysiology to prevention and management.Semantic proximity Read ↗

Type-2 diabetes: a cocktail of genetic discoverySemantic proximity Read ↗

Type 2 diabetes: pathogenesis and treatmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.