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Article

The pathophysiology of type 2 diabetes mellitus: an overview.

Acta physiologica Scandinavica - 1 Mar 2001

Ostenson C G

Abstract excerpt

Type 2 diabetes mellitus is a heterogeneous disorder characterized by chronic hyperglycaemia. The aetiological heterogeneity is suggested by genetic inheritance and its interplay with environmental factors. Impaired insulin secretion and decreased insulin sensitivity are the main pathophysiological features, responsible for development of hyperglycaemia in type 2 diabetes. However, the genetic basis of these...

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PMID: 11412136
DOI: 10.1046/j.1365-201x.2001.00826.x

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