Article
The analysis of p53 tumor suppressor gene in pineal parenchymal tumors.
Noshuyo byori = Brain tumor pathology - 1 Mar 1995
Tsumanuma I, Sato M, Okazaki H, Tanaka R, Washiyama K, Kawasaki T, Kumanishi T
Abstract excerpt
p53 gene mutation was examined in 9 pineal parenchymal tumors, 4 pineoblastomas and 5 pineocytomas, by the immunohistochemical and the polymerase chain reaction-mediated single strand conformation polymorphism (PCR-SSCP) analyses. In each case, immunohistochemical analysis revealed no positive staining for p53 protein with either PAb1801 or DO-1 antibody and PCR-SSCP analysis revealed no abnormal migration in...
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