Article
nfxB as a novel target for analysis of mutation spectra in Pseudomonas aeruginosa.
PloS one - 1 Jan 2013
Monti Mariela R, Morero Natalia R, Miguel Virginia, Argaraña Carlos E
Abstract excerpt
nfxB encodes a negative regulator of the mexCD-oprJ genes for drug efflux in the opportunistic pathogen Pseudomonas aeruginosa. Inactivating mutations in this transcriptional regulator constitute one of the main mechanisms of resistance to ciprofloxacin (Cip(r)). In this work, we evaluated the us...
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