Occurrence of the nfxB type mutation in clinical isolates of Pseudomonas aeruginosa.

doi:10.1128/AAC.36.11.2562

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Article

Occurrence of the nfxB type mutation in clinical isolates of Pseudomonas aeruginosa.

Antimicrobial agents and chemotherapy - 1 Nov 1992

Jakics E B, Iyobe S, Hirai K, Fukuda H, Hashimoto H

Abstract excerpt

Seven spontaneous norfloxacin (NFLX)-resistant mutants obtained in vitro from 20 NFLX-susceptible clinical isolates and 3 NFLX-resistant clinical isolates of Pseudomonas aeruginosa were transformed with the pNF111 plasmid, whose BamHI fragment is responsible for conferring susceptibility to NFLX,...

Topics

Carbenicillin
Chloramphenicol
Drug Resistance, Microbial
Genes, Bacterial
Gentamicins
Imipenem
Microbial Sensitivity Tests
Mutation
Norfloxacin
Phenotype
Plasmids
Pseudomonas aeruginosa
Transformation, Bacterial

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