Article
mvaT mutation modifies the expression of the Pseudomonas aeruginosa multidrug efflux operon mexEF-oprN.
FEMS microbiology letters - 1 Feb 2006
Westfall Landon W, Carty Nancy L, Layland Nancy, Kuan Phillip, Colmer-Hamood Jane A, Hamood Abdul N
Abstract excerpt
Pseudomonas aeruginosa carries several multidrug efflux operons, including mexEF-oprN, that contribute to its resistance to multiple antibiotics. mvaT affects the expression of several P. aeruginosa genes. In this study, we show that the mvaT mutant PAODeltamvaT is more resistant than its parent PAO1 strain to chloramphenicol and norfloxacin but more sensitive to imipenem; yet both were less resistant to...
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