Evidence for impaired retinoic acid receptor-thyroid hormone receptor AF-2 cofactor activity in human lung cancer.

doi:10.1128/MCB.15.7.3945

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Article

Evidence for impaired retinoic acid receptor-thyroid hormone receptor AF-2 cofactor activity in human lung cancer.

Molecular and cellular biology - 1 Jul 1995

Moghal N, Neel B G

Abstract excerpt

Retinoic acid (RA) is required for normal airway epithelial cell growth and differentiation both in vivo and in vitro. One of the earliest events following the exposure of bronchial epithelial cells to RA is the strong induction of RA receptor beta (RAR beta) mRNA. Previous work established that...

Topics

Adenovirus E1A Proteins
Base Sequence
DNA-Binding Proteins
Gene Expression Regulation, Neoplastic
Genetic Complementation Test
Humans
Isomerism
Lung Neoplasms
Models, Genetic
Molecular Sequence Data
Mutation
Receptors, Retinoic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Thyroid Hormone

Regulatory Sequences, Nucleic Acid

TATA-Box Binding Protein

Transcription Factors

Transcription, Genetic

Transcriptional Activation

Source

Open in PubMed Open full text

Identifiers

PMID: 7791800
DOI: 10.1128/MCB.15.7.3945
PMCID: PMC230634

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7791800-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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