Article
Tumor-suppressive effect of the retinoic acid receptor beta in human epidermoid lung cancer cells.
1 Feb 1993
Abstract excerpt
Retinoic acid receptor beta (RAR beta), which codes for a nuclear receptor for retinoic acid, is localized in a chromosomal region frequently deleted in lung cancer cells. The gene is expressed in normal lung tissue and in the majority of the cell lines derived from lung tumors but not in most of the lines derived from lung tumors with epidermoid characteristics. To study the possible role of RAR beta in growth...
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