Article
E-box variants direct formation of distinct complexes with the basic helix-loop-helix protein ALF1.
Journal of molecular biology - 9 Jun 1995
Bonven B J, Nielsen A L, Nørby P L, Pedersen F S, Jørgensen P
Abstract excerpt
The murine transcription factor ALF1 belongs to the class of basic helix-loop-helix proteins specific for the NCAGNTGN-version of the E-box. Binding of homodimeric ALF1 to variants of this motif was studied by a combination of binding site selection technology and DNA modification interference an...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Basic Helix-Loop-Helix Transcription Factors
- Basic-Leucine Zipper Transcription Factors
- Binding Sites
- DNA
- DNA-Binding Proteins
- Escherichia coli
- Genetic Variation
- Helix-Loop-Helix Motifs
- Mice
- Models, Molecular
- Molecular Sequence Data
- Nucleic Acid Conformation
- Polymerase Chain Reaction
- Saccharomyces cerevisiae