Article
A sequence-induced superhelical DNA segment serves as transcriptional enhancer.
Journal of molecular biology - 10 Feb 1995
Brahms G, Brahms S, Magasanik B
Abstract excerpt
The initiation of transcription at the sigma 54-dependent promoter glnAp2 of Escherichia coli is activated by the protein NR1(NTRC)-phosphate, which binds to two sites located upstream of the promoter that together constitute an enhancer. The cooperative binding facilitates the oligomerization of...
Topics
- Adenosine Triphosphatases
- Bacterial Proteins
- Base Sequence
- Binding Sites
- DNA, Superhelical
- DNA-Binding Proteins
- DNA-Directed RNA Polymerases
- Enhancer Elements, Genetic
- Escherichia coli
- Escherichia coli Proteins
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- PII Nitrogen Regulatory Proteins
- Phosphorylation
- Promoter Regions, Genetic
- RNA Polymerase Sigma 54
- Sigma Factor