Article
The acidic C-terminal domain and A-box of HMGB-1 regulates p53-mediated transcription.
Nucleic acids research - 15 Jun 2003
Banerjee Sourav, Kundu Tapas K
Abstract excerpt
p53 function is modulated by several covalent and non-covalent modifiers. The architectural DNA- binding protein, High Mobility Group protein B-1 is a unique activator of p53. HMGB-1 protein is structured into two HMG-box domains, namely A-box and B-box, connected to a long highly acidic C-termin...
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