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Article

Genetic refinement of the chromosome 5q lattice corneal dystrophy type I locus to within a 2 cM interval.

Journal of medical genetics - 1 Mar 1995

Gregory C Y, Evans K, Bhattacharya S S

Abstract excerpt

Lattice corneal dystrophy type I (LCDI) is a relatively common corneal dystrophy which can cause severe visual impairment. Recent studies have suggested a genetic localisation for the disease to chromosome 5q. Independent genetic linkage analysis in a six generation LCDI pedigree confirmed linkage to the 5q region bounded by marker loci IL9 and D5S436 suggesting genetic homogeneity. A maximum two point lod score...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 5
Corneal Dystrophies, Hereditary
Family Health
Female
Genetic Carrier Screening
Genetic Linkage
Genetic Markers
Humans
Likelihood Functions
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Pedigree

Phenotype

Population

Source

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Identifiers

PMID: 7783175
DOI: 10.1136/jmg.32.3.224
PMCID: PMC1050323

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7783175-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Genetic refinement of the chromosome 5q lattice corneal dystrophy type I locus to within a 2 cM interval.PMID 7783175Read ↗

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