Three autosomal dominant corneal dystrophies map to chromosome 5q.

doi:10.1038/ng0194-47

Article

Three autosomal dominant corneal dystrophies map to chromosome 5q.

Nature genetics - 1 Jan 1994

Stone E M, Mathers W D, Rosenwasser G O, Holland E J, Folberg R, Krachmer J H, Nichols B E, Gorevic P D, Taylor C M, Streb L M

Abstract excerpt

The two most common autosomal dominant dystrophies of the corneal stroma are lattice corneal dystrophy type I and granular dystrophy. A third autosomal dominant stromal dystrophy (Avellino) has also been recognized. Chromosome linkage analysis of four families with Avellino dystrophy mapped the d...

Topics

Alleles
Amyloid
Chromosome Mapping
Chromosomes, Human, Pair 5
Corneal Dystrophies, Hereditary
Female
Genes, Dominant
Genetic Linkage
Genetic Markers
Humans
Italy
Lod Score
Male
Pedigree
United States

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