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Article

Genomewide linkage scan in a multigeneration Caucasian pedigree identifies a novel locus for keratoconus on chromosome 5q14.3-q21.1.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000

Tang Yongming G, Rabinowitz Yaron S, Taylor Kent D, Li Xiaohui, Hu Mingshu, Picornell Yoana, Yang Huiying

Abstract excerpt

PURPOSE: Keratoconus is a corneal dystrophy with an incidence of 1 in 2000 and a leading cause for cornea transplantation in Western developed countries. Both clinical observations and segregation analyses suggest a major role for genes in its pathogenesis. It is genetically heterogeneous, most commonly sporadic, but inherited patterns with recessive or dominant modes have also been reported. We studied a...

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PMID: 16024971
DOI: 10.1097/01.gim.0000170772.41860.54

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Genomewide linkage scan in a multigeneration Caucasian pedigree identifies a novel locus for keratoconus on chromosome 5q14.3-q21.1.PMID 16024971Read ↗

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