Article
Further refinement of the MYP2 locus for autosomal dominant high myopia by linkage disequilibrium analysis.
Ophthalmic genetics - 1 Jun 2001
Young T L, Atwood L D, Ronan S M, Dewan A T, Alvear A B, Peterson J, Holleschau A, King R A
Abstract excerpt
INTRODUCTION: High myopia (>-6.00 diopters) is a complex common disorder that predisposes individuals to retinal detachment, glaucoma, macular degeneration, and premature cataracts. A recent linkage analysis of seven families with autosomal dominant high myopia has identified one locus (MYP2) for high myopia on chromosome 18p11.31 (Young et al.: Am J Hum Genet 1998;63:109-119). Haplotype analysis revealed an...
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