Article
Exploring the dense mapping of a region of potential linkage in complex disease: an example in multiple sclerosis.
Genetic epidemiology - 1 Jan 1999
Feakes R, Sawcer S, Chataway J, Coraddu F, Broadley S, Gray J, Jones H B, Clayton D, Goodfellow P N, Compston A
Abstract excerpt
In 1996 we reported the results of a genome screen in multiple sclerosis, in which potential linkage was identified in a total of twenty regions, including the centromeric region of chromosome 5. In order to investigate the efficiency of typing dense arrays of markers in regions of potential linkage, we have typed an additional nineteen microsatellite markers from this chromosome 5 region (D5S623 - D5S428) in the...
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