Article
Use of a CEPH meiotic breakpoint panel to refine the locus of limb-girdle muscular dystrophy type 1A (LGMD1A) to a 2-Mb interval on 5q31.
Genomics - 1 Dec 1998
Bartoloni L, Horrigan S K, Viles K D, Gilchrist J M, Stajich J M, Vance J M, Yamaoka L H, Pericak-Vance M A, Westbrook C A, Speer M C
Abstract excerpt
Limb-girdle muscular dystrophy type 1A (LGMD1A) is an autosomal dominant disease characterized by progressive weakness of the hip and shoulder girdle. The gene for LGMD1A had been localized to a 7-cM interval at 5q31 in a single large family (Family 39). To refine the localization of LGMD1A furth...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 5
- Female
- Genes
- Genetic Linkage
- Genetic Markers
- Genotype
- Haplotypes
- Humans
- Male
- Meiosis
- Muscular Dystrophies
- Pedigree
- Physical Chromosome Mapping