Article
Use of a CEPH meiotic breakpoint panel to refine the locus of limb-girdle muscular dystrophy type 1A (LGMD1A) to a 2-Mb interval on 5q31.
Genomics - 1 Dec 1998
Bartoloni L, Horrigan S K, Viles K D, Gilchrist J M, Stajich J M, Vance J M, Yamaoka L H, Pericak-Vance M A, Westbrook C A, Speer M C
Abstract excerpt
Limb-girdle muscular dystrophy type 1A (LGMD1A) is an autosomal dominant disease characterized by progressive weakness of the hip and shoulder girdle. The gene for LGMD1A had been localized to a 7-cM interval at 5q31 in a single large family (Family 39). To refine the localization of LGMD1A further and to aid in its identification, a high-resolution physical map of the locus was used to identify and provisionally...
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