Article
Mapping of Reis-Bücklers' corneal dystrophy to chromosome 5q.
American journal of ophthalmology - 1 Apr 1996
Small K W, Mullen L, Barletta J, Graham K, Glasgow B, Stern G, Yee R
Abstract excerpt
PURPOSE: Recently several autosomal dominant corneal stromal dystrophies have been mapped to chromosome 5q. Therefore, we tested whether Reis-Bücklers' corneal dystrophy, an autosomal dominant trait, was also linked to the same region. METHODS: Five generations of a single family with Reis-Bückle...
Topics
- Basement Membrane
- Chromosome Mapping
- Chromosomes, Human, Pair 5
- Corneal Dystrophies, Hereditary
- Corneal Stroma
- Female
- Gene Frequency
- Genetic Linkage
- Humans
- Male
- Mutation
- Pedigree