Article
The bli-4 locus of Caenorhabditis elegans encodes structurally distinct kex2/subtilisin-like endoproteases essential for early development and adult morphology.
Genes & development - 15 Apr 1995
Thacker C, Peters K, Srayko M, Rose A M
Abstract excerpt
Many secreted proteins are excised from inactive proproteins by cleavage at pairs of basic residues. Recent studies have identified several serine endoproteases that catalyze this cleavage in the secretory pathways of yeast and metazoans. These enzymes belong to the kex2/subtilisin-like family of...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Chromosome Mapping
- Cloning, Molecular
- Conserved Sequence
- Cosmids
- Gene Expression
- Genes, Helminth
- Genes, Lethal
- Molecular Sequence Data
- Mutation
- Proprotein Convertases
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae Proteins