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Article

Caenorhabditis elegans dpy-5 is a cuticle procollagen processed by a proprotein convertase.

Cellular and molecular life sciences : CMLS - 1 May 2006

Thacker C, Sheps J A, Rose A M

Abstract excerpt

Genetic analysis of the nematode Caenorhabditis elegans reveals that all dpy-5 alleles are dominant suppressors of bli-4 blistering. Molecular cloning of dpy-5 establishes that it encodes a cuticle procollagen, defects in which are responsible for the short-body, dumpy phenotype. The null mutation, e907 removes the entire coding region, whereas the dpy-5 reference allele, e61, contains a nonsense substitution....

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Identifiers

PMID: 16649143
DOI: 10.1007/s00018-006-6012-z
PMCID: PMC11136371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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