Article
Caenorhabditis elegans dpy-5 is a cuticle procollagen processed by a proprotein convertase.
Cellular and molecular life sciences : CMLS - 1 May 2006
Thacker C, Sheps J A, Rose A M
Abstract excerpt
Genetic analysis of the nematode Caenorhabditis elegans reveals that all dpy-5 alleles are dominant suppressors of bli-4 blistering. Molecular cloning of dpy-5 establishes that it encodes a cuticle procollagen, defects in which are responsible for the short-body, dumpy phenotype. The null mutation, e907 removes the entire coding region, whereas the dpy-5 reference allele, e61, contains a nonsense substitution....
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Molecular Sequence Data
- Mutation
- Procollagen
- Proprotein Convertases