Article
The N-glycanase png-1 acts to limit axon branching during organ formation in Caenorhabditis elegans.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Feb 2010
Habibi-Babadi Nasrin, Su Anna, de Carvalho Carlos E, Colavita Antonio
Abstract excerpt
Peptide:N-glycanases (PNGases) are cytoplasmic de-N-glycosylation enzymes that have been shown in cultured cells to facilitate the degradation of misfolded glycoproteins during endoplasmic reticulum-associated degradation and in the processing of major histocompatibility complex class I antigens for proper cell-surface presentation. The gene encoding PNGase activity was initially described in budding yeast...
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