Article
Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins.
The Biochemical journal - 1 Nov 1997
Nakayama K
Abstract excerpt
Limited endoproteolysis of inactive precursor proteins at sites marked by paired or multiple basic amino acids is a widespread process by which biologically active peptides and proteins are produced within the secretory pathway in eukaryotic cells. The identification of a novel family of endoprot...
Topics
- Amino Acid Sequence
- Animals
- Enzyme Inhibitors
- Furin
- Gene Expression
- Genetic Diseases, Inborn
- Humans
- Molecular Sequence Data
- Mutation
- Proprotein Convertases
- Protein Precursors
- Recombinant Proteins