Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The let-268 locus of Caenorhabditis elegans encodes a procollagen lysyl hydroxylase that is essential for type IV collagen secretion.

Developmental biology - 15 Nov 2000

Norman K R, Moerman D G

Abstract excerpt

Basement membranes are thin sheets of specialized extracellular matrix molecules that are important for supplying mechanical support and for providing an interactive surface for cell morphology. Prior to secretion and assembly, basement membrane molecules undergo intracellular processing, which is essential for their function. We have identified several mutations in a procollagen processing enzyme, lysyl...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actin Cytoskeleton
Share to Basement Membrane
Share to Collagen

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Helminth

Share to Heparan Sulfate Proteoglycans

Share to Muscle Contraction

Share to Procollagen

Share to Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase

Source

Identifiers

PMID: 11071784
DOI: 10.1006/dbio.2000.9897

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The let-268 locus of Caenorhabditis elegans encodes a procollagen lysyl hydroxylase that is essential for type IV collagen secretion.PMID 11071784Read ↗

Structures and functions of collagens in Caenorhabditis elegans.Semantic proximity Read ↗

dpy-18 encodes an alpha-subunit of prolyl-4-hydroxylase in caenorhabditis elegans.Semantic proximity Read ↗

Collagens, modifying enzymes and their mutations in humans, flies and worms.Semantic proximity Read ↗

Embryonic lethality caused by mutations in basement membrane collagen of C. elegans.Semantic proximity Read ↗

Structural and physiological functions of Caenorhabditis elegans epidermisSemantic proximity Read ↗

Prolyl 4-hydroxylase is an essential procollagen-modifying enzyme required for exoskeleton formation and the maintenance of body shape in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes.Semantic proximity Read ↗

Regulation of axonal midline guidance by prolyl 4-hydroxylation in Caenorhabditis elegans.Semantic proximity Read ↗

Characterization of alpha1(IV) collagen mutations in Caenorhabditis elegans and the effects of alpha1 and alpha2(IV) mutations on type IV collagen distribution.Semantic proximity Read ↗

Caenorhabditis elegans dpy-5 is a cuticle procollagen processed by a proprotein convertase.Semantic proximity Read ↗

Mutations in the alpha 2(IV) basement membrane collagen gene of Caenorhabditis elegans produce phenotypes of differing severities.Semantic proximity Read ↗

A complete collagen IV fluorophore knock-in toolkit reveals α-chain diversity in basement membraneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.