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Article

Functional genomics in Caenorhabditis elegans: An approach involving comparisons of sequences from related nematodes.

Genome research - 1 Apr 1999

Thacker C, Marra M A, Jones A, Baillie D L, Rose A M

Abstract excerpt

Comparative genomic analysis was used to investigate the gene structure of the bli-4 locus from two related Caenorhabditis species, C. elegans and C. briggsae. In C. elegans, bli-4 is a complex gene encoding a member of the kex2/subtilisin-like family of proprotein convertases. Genomic sequence comparisons coupled with RT-PCR analysis identified five additional coding exons that had not been identified previously...

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PMID: 10207157
PMCID: PMC310735

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