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Article

Relations between deletion polymorphism of the angiotensin-converting enzyme gene and insulin resistance, glucose intolerance, hyperinsulinemia, and dyslipidemia.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 1995

Katsuya T, Horiuchi M, Chen Y D, Koike G, Pratt R E, Dzau V J, Reaven G M

Abstract excerpt

Recent reports have shown that the frequency of the homozygous deletion genotype (DD) of the angiotensin-converting enzyme (ACE) gene is highly associated with myocardial infarction and cardiomyopathy, particularly in those considered to be at low risk for coronary heart disease (CHD) on the basis of their apoB or LDL cholesterol concentrations. The present study was initiated to extend this inquiry by exploring...

Topics

Base Sequence
Body Mass Index
Coronary Disease
Diabetes Mellitus, Type 2
Female
Gene Deletion
Genotype
Glucose Tolerance Test
Humans
Hyperlipidemias

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin

Insulin Resistance

Male

Middle Aged

Molecular Sequence Data

Peptidyl-Dipeptidase A

Polymorphism, Genetic

Risk Factors

Source

Identifiers

PMID: 7773733
DOI: 10.1161/01.atv.15.6.779

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7773733-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Relations between deletion polymorphism of the angiotensin-converting enzyme gene and insulin resistance, glucose intolerance, hyperinsulinemia, and dyslipidemia.PMID 7773733Read ↗

Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM.Semantic proximity Read ↗

Influence of the ACE Gene Insertion/Deletion Polymorphism on Insulin Sensitivity and Impaired Glucose Tolerance in Healthy SubjectsSemantic proximity Read ↗

The insertion/deletion polymorphism of the ACE gene is related to insulin sensitivity in overweight women.Semantic proximity Read ↗

Deletion polymorphism of angiotensin-converting enzyme gene is associated with postprandial hyperglycaemia in individuals undergoing general check-up.Semantic proximity Read ↗

The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance?Semantic proximity Read ↗

Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with increased plasma angiotensin-converting enzyme activity but not with increased risk for myocardial infarction and coronary artery disease.Semantic proximity Read ↗

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction.Semantic proximity Read ↗

UK prospective diabetes study (UKPDS) 14: association of angiotensin-converting enzyme insertion/deletion polymorphism with myocardial infarction in NIDDM.Semantic proximity Read ↗

Angiotensin-1-converting enzyme (ACE) gene polymorphism, plasma ACE levels, and their association with the metabolic syndrome and electrocardiographic coronary artery disease in Pima Indians.Semantic proximity Read ↗

Association between the angiotensin converting enzyme gene insertion/deletion polymorphism and metabolic disturbances in women with polycystic ovary syndrome.Semantic proximity Read ↗

Angiotensin-converting enzyme gene and diabetes mellitus.Semantic proximity Read ↗

Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene in patients with hypertension, non-insulin-dependent diabetes mellitus, and coronary heart disease in Taiwan.Semantic proximity Read ↗

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