Article
Association between the angiotensin converting enzyme gene insertion/deletion polymorphism and metabolic disturbances in women with polycystic ovary syndrome.
Molecular medicine reports - 1 Dec 2016
Ożegowska Katarzyna, Bogacz Anna, Bartkowiak-Wieczorek Joanna, Seremak-Mrozikiewicz Agnieszka, Pawelczyk Leszek
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age. A number of PCOS complications may be associated with the elevated level of angiotensin II and low bradykinin concentrations. The aim of the present study was to investigate the frequencies of angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphisms in women with PCOS and to determine the...
Topics
- Adult
- Alleles
- Biomarkers
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- INDEL Mutation
- Odds Ratio
- Peptidyl-Dipeptidase A
- Polycystic Ovary Syndrome