Article
Deletion polymorphism of angiotensin-converting enzyme gene is associated with postprandial hyperglycaemia in individuals undergoing general check-up.
Clinical and experimental pharmacology & physiology - 1 Jul 2000
Ohishi M, Rakugi H, Miki T, Katsuya T, Okamura A, Kamide K, Nakata Y, Takami S, Ikegami H, Yanagitani Y, Tabuchi Y, Kumahara Y, Higaki J, Ogihara T
Abstract excerpt
1. Deletion polymorphism, DD, of the angiotensin-converting enzyme (ACE) gene is reported to be related to cardiovascular disease, which is frequently based on insulin resistance. 2. To clarify the relationship between the ACE genotype DD and plasma glucose increases after an oral glucose load, we performed 75 g oral glucose tolerance test (OGTT) in 301 nondiabetic men (age range 30-60 years) undergoing general...
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