Article
Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM.
Human genetics - 1 Mar 1998
Huang X H, Rantalaiho V, Wirta O, Pasternack A, Koivula T, Hiltunen T, Nikkari T, Lehtimäki T
Abstract excerpt
The deletion (D) allele of the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism has been shown to be associated with cardiovascular and renal diseases in diabetes mellitus, but the mechanism underlying this association is not known. In addition, recent studies of the...
Topics
- Diabetes Mellitus, Type 2
- Female
- Gene Frequency
- Genotype
- Glucose Intolerance
- Humans
- Hypertension
- Insulin Resistance
- Male
- Matched-Pair Analysis
- Middle Aged
- Peptidyl-Dipeptidase A
- Polymerase Chain Reaction
- Polymorphism, Genetic