Article
Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene in patients with hypertension, non-insulin-dependent diabetes mellitus, and coronary heart disease in Taiwan.
Metabolism: clinical and experimental - 1 Oct 1997
Chuang L M, Chiu K C, Chiang F T, Lee K C, Wu H P, Lin B J, Tai T Y
Abstract excerpt
An insertion/deletion (I/D) polymorphism of the angiotensin I-converting enzyme (ACE) gene has been identified that determines most of the plasma ACE activity genetically. Association of the D allele with insulin sensitivity and of the D/D genotype with coronary heart disease (CHD) has been repor...
Topics
- Age of Onset
- Alleles
- Analysis of Variance
- Coronary Disease
- DNA
- DNA Primers
- DNA Transposable Elements
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Ethnicity
- Female