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Article

The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance?

Circulation - 15 Dec 1995

Panahloo A, Andrès C, Mohamed-Ali V, Gould M M, Talmud P, Humphries S E, Yudkin J S

Abstract excerpt

BACKGROUND: The insertion/deletion (ID) polymorphism of the angiotensin-converting enzyme (ACE) gene has been associated with increased coronary heart disease (CHD), although the mechanism of this association is not apparent. We tested the hypothesis that the deletion allele of the ACE gene is associated with insulin resistance. METHODS AND RESULTS: We related ACE genotype to components of the insulin-resistance...

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Source

Identifiers

PMID: 8521557
DOI: 10.1161/01.cir.92.12.3390

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance?PMID 8521557Read ↗

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The insertion/deletion polymorphism of the ACE gene is related to insulin sensitivity in overweight women.Semantic proximity Read ↗

The insertion allele at the angiotensin I-converting enzyme gene locus is associated with insulin resistance.Semantic proximity Read ↗

Relations between deletion polymorphism of the angiotensin-converting enzyme gene and insulin resistance, glucose intolerance, hyperinsulinemia, and dyslipidemia.Semantic proximity Read ↗

Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM.Semantic proximity Read ↗

Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with increased plasma angiotensin-converting enzyme activity but not with increased risk for myocardial infarction and coronary artery disease.Semantic proximity Read ↗

UK prospective diabetes study (UKPDS) 14: association of angiotensin-converting enzyme insertion/deletion polymorphism with myocardial infarction in NIDDM.Semantic proximity Read ↗

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