Article
Genes for beta-lactam antibiotic biosynthesis.
Antonie van Leeuwenhoek - 1 Jan 1995
Martín J F, Gutiérrez S
Abstract excerpt
The genes pcbAB, pcbC and penDE encoding enzymes involved in the biosynthesis of penicillin have been cloned from Penicillium chrysogenum and Aspergillus nidulans. They are clustered in chromosome I (10.4 Mb) of P. chrysogenum, but they are located in chromosome II of Penicillium notatum (9.6 Mb) and in chromosome VI (3.0 Mb) of A. nidulans. Expression studies have shown that each gene is expressed as a single...
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