Article
Ethnic differences in the prevalence of the homozygous deleted genotype of glutathione S-transferase theta.
Carcinogenesis - 1 May 1995
Nelson H H, Wiencke J K, Christiani D C, Cheng T J, Zuo Z F, Schwartz B S, Lee B K, Spitz M R, Wang M, Xu X
Abstract excerpt
In humans the glutathione S-transferase (GST) genes encode four classes of proteins (GST) important in the detoxification of reactive electrophiles. Recently, a gene deletion polymorphism was discovered within the GST class theta locus that leads to a functional deficiency in GST theta activity within circulating red blood cells. In this study we have examined the ethnic distribution of this polymorphism using a...
Topics
- Asian People
- Base Sequence
- Black People
- China
- Cytochrome P-450 Enzyme System
- DNA Primers
- Ethnicity
- Gene Deletion
- Genotype
- Glutathione Transferase
- Hispanic or Latino