Article
Concordance between enzyme activity and genotype of glutathione S-transferase theta (GSTT1).
Biochemical pharmacology - 1 Nov 1998
Bruhn C, Brockmöller J, Kerb R, Roots I, Borchert H H
Abstract excerpt
Blood samples from 140 healthy German volunteers were used to further characterize the genetic polymorphism of the human theta class glutathione S-transferase 1 (GSTT1). For measurements of GSTT1 activity, hemolysates were incubated in vitro with different concentrations of dichloromethane. The resulting enzymatically mediated production of formaldehyde was determined colorimetrically by the Nash reaction. GSTT1...
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