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Article

Worldwide Systematic Review of GSTM1 and GSTT1 Null Genotypes by Continent, Ethnicity, and Therapeutic Area.

Omics : a journal of integrative biology - 1 Oct 2022

Nakanishi Giovana, Pita-Oliveira Murilo, Bertagnolli Laísa S, Torres-Loureiro Sabrina, Scudeler Mariana M, Cirino Heithor S, Chaves Maria Laura, Miwa Bruno, Rodrigues-Soares Fernanda

Abstract excerpt

Glutathione S-transferase Mu 1 (GSTM1) and glutathione S-transferase theta 1 (GSTT1) enzymes are glutathione-S-transferases with broad significance for susceptibility or resistance to multifactorial human diseases, as well as detoxification of environmental chemicals and drugs. Moreover, some individuals may have a complete deletion of GSTM1 and GSTT1 genes, which can contribute to patient-to-patient variability...

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Identifiers

PMID: 36112350
DOI: 10.1089/omi.2022.0090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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