Article
The crypt cycle and the asymptotic dynamics of the proportion of differently sized mutant crypt clones in the mouse intestine.
Proceedings. Biological sciences - 22 Apr 1995
Bjerknes M
Abstract excerpt
The dynamics of clones of intestinal epithelial crypts populated by mutant stem cells offers the hope of new and independent evidence of continued crypt replication throughout adult life, an important prediction of recent models of intestinal stem cell biology. It is shown here that the experimen...
Topics
- Animals
- Cell Cycle
- Cell Size
- Clone Cells
- Intestinal Mucosa
- Intestine, Small
- Mice
- Models, Biological
- Mutation