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Article

Intestinal Stem Cell Dynamics: A Story of Mice and Humans.

Cell stem cell - 1 Jun 2018

Hodder Michael C, Flanagan Dustin J, Sansom Owen J

Abstract excerpt

Stem cell dynamics define the probability of accumulating mutations within the intestinal epithelium. In this issue of Cell Stem Cell, Nicholson et al. (2018) report that human intestinal stem cell dynamics differ significantly from those of mice and establish that oncogenic mutations are more likely to expand; therefore, "normal" epithelium may carry multiple mutations.

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Identifiers

PMID: 29859166
DOI: 10.1016/j.stem.2018.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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