Article
Stem cell kinetics and intestinal cancer.
Anticancer research - 1 Jan 2000
Morris J A
Abstract excerpt
The conventional view that intestinal stem cells divide every few days so that each stem cell undergoes several thousand divisions in a lifetime is challenged. It is proposed that fully differentiated cells, even in old age, are no more than sixty divisions from the zygote. This concept leads to...
Topics
- Aged
- Aging
- Animals
- Cell Cycle
- Humans
- Intestinal Neoplasms
- Intestines
- Male
- Mice
- Models, Biological
- Mutation
- Stem Cells
