Article
Close linkage of fragile X-mental retardation syndrome to haemophilia B and transmission through a normal male.
Nature - 1 Jan 2000
Camerino G, Mattei M G, Mattei J F, Jaye M, Mandel J L
Abstract excerpt
The fragile X-mental retardation syndrome is defined by a moderate to severe mental retardation associated with a cytogenetic marker, a fragile site localized on the long arm of the X chromosome at band Xq 27. This syndrome has recently been recognized as one of the major causes of genetically determined mental retardation, and as one of the most important X-linked diseases with respect to its frequency...
Topics
- Adolescent
- Adult
- Alleles
- Child
- Child, Preschool
- DNA
- Factor IX
- Female
- Genes
- Hemophilia A
- Humans
- Infant
- Intellectual Disability