Evidence against close linkage of unipolar affective illness to human chromosome 11p markers HRAS1 and INS and chromosome Xq marker DXS52.

doi:10.1016/0006-3223(90)90433-3

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Article

Evidence against close linkage of unipolar affective illness to human chromosome 11p markers HRAS1 and INS and chromosome Xq marker DXS52.

Biological psychiatry - 1 Jul 1990

Neiswanger K, Slaugenhaupt S A, Hughes H B, Frank E, Frankel D R, McCarty M J, Chakravarti A, Zubenko G S, Kupfer D J, Kaplan B B

Abstract excerpt

The genetic basis of various subtypes of the affective disorders has been investigated by family, twin, and adoption studies, as well as by segregation and linkage analysis. Linkage analyses of bipolar disorder with the chromosome 11p15 DNA markers HRAS1 and INS, and the chromosome Xq28 markers f...

Topics

Bipolar Disorder
Chromosomes, Human, Pair 11
DNA
Depressive Disorder
Genetic Linkage
Genetic Markers
Humans
Pedigree
Phenotype
Polymorphism, Restriction Fragment Length
Risk Factors
Sex Chromosome Aberrations
X Chromosome

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PMID: 1973904
DOI: 10.1016/0006-3223(90)90433-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1973904-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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