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Article

Evidence against close linkage of unipolar affective illness to human chromosome 11p markers HRAS1 and INS and chromosome Xq marker DXS52.

Biological psychiatry - 1 Jul 1990

Neiswanger K, Slaugenhaupt S A, Hughes H B, Frank E, Frankel D R, McCarty M J, Chakravarti A, Zubenko G S, Kupfer D J, Kaplan B B

Abstract excerpt

The genetic basis of various subtypes of the affective disorders has been investigated by family, twin, and adoption studies, as well as by segregation and linkage analysis. Linkage analyses of bipolar disorder with the chromosome 11p15 DNA markers HRAS1 and INS, and the chromosome Xq28 markers for color blindness and G6PD have been reported. We have used restriction fragment length polymorphisms as markers to...

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Source

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PMID: 1973904
DOI: 10.1016/0006-3223(90)90433-3

Genes

INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Evidence against close linkage of unipolar affective illness to human chromosome 11p markers HRAS1 and INS and chromosome Xq marker DXS52.PMID 1973904Read ↗

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