Article
Serum induction of MEF2/RSRF expression in vascular myocytes is mediated at the level of translation.
Molecular and cellular biology - 1 Jun 1995
Suzuki E, Guo K, Kolman M, Yu Y T, Walsh K
Abstract excerpt
Vascular smooth muscle cells (VSMCs) reversibly coordinate the expression of VSMC-specific genes and the genes required for cell cycle progression. Here we demonstrate that isoforms of the MEF2/RSRF transcription factor are expressed in VSMCs and in vascular tissue. The MEF2A DNA-binding activity was upregulated when quiescent VSMCs were stimulated to proliferate with serum mitogens. The serum-induction of MEF2A...
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