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Article

Fibroblast Growth Factor 12 Is a Novel Regulator of Vascular Smooth Muscle Cell Plasticity and Fate.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2016

Song Sun-Hwa, Kim Kyungjong, Jo Eun-Kyung, Kim Young-Wook, Kwon Jin-Sook, Bae Sun Sik, Sung Jong-Hyuk, Park Sang Gyu, Kim Jee Taek, Suh Wonhee

Abstract excerpt

OBJECTIVE: Vascular smooth muscle cells (VSMCs) modulate their phenotype between synthetic and contractile states in response to environmental changes; this modulation plays a crucial role in the pathogenesis of restenosis and atherosclerosis. Here, we identified fibroblast growth factor 12 (FGF12) as a novel key regulator of the VSMC phenotype switch. APPROACH AND RESULTS: Using murine models and human...

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Source

Identifiers

PMID: 27470512
DOI: 10.1161/ATVBAHA.116.308017

Genes

FGF12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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