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Article

14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner.

Molecular and cellular biology - 1 Jun 1995

Michaud N R, Fabian J R, Mathes K D, Morrison D K

Abstract excerpt

Recent reports have demonstrated the in vivo association of Raf-1 with members of the 14-3-3 protein family. To address the significance of the Raf-1-14-3-3 interaction, we investigated the enzymatic activity and biological function of Raf-1 in the presence and absence of associated 14-3-3. The i...

Topics

14-3-3 Proteins
Animals
Cell Line
Enzyme Activation
Humans
Mutation
Phosphorylation
Protein Serine-Threonine Kinases
Proteins
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-raf
Tyrosine 3-Monooxygenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7760835
DOI: 10.1128/MCB.15.6.3390
PMCID: PMC230573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7760835-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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